Ischemia and Reperfusion Induce Differential Expression of Calpastatin and Its Homologue High Molecular Weight Calmodulin-Binding Protein in Murine Cardiomyocytes

In the heart, calpastatin (Calp) and its homologue high molecular weight calmodulin-binding protein (HMWCaMBP) regulate calpains (Calpn) by inhibition. A rise in intracellular myocardial Ca(2+) during cardiac ischemia activates Calpn thereby causing damage to myocardial proteins, which leads to myoc...

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Detalles Bibliográficos
Autores principales: Parameswaran, Sreejit, Sharma, Rajendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259361/
https://www.ncbi.nlm.nih.gov/pubmed/25486053
http://dx.doi.org/10.1371/journal.pone.0114653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259361/
https://www.ncbi.nlm.nih.gov/pubmed/25486053
http://dx.doi.org/10.1371/journal.pone.0114653

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