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Ischemia and Reperfusion Induce Differential Expression of Calpastatin and Its Homologue High Molecular Weight Calmodulin-Binding Protein in Murine Cardiomyocytes

In the heart, calpastatin (Calp) and its homologue high molecular weight calmodulin-binding protein (HMWCaMBP) regulate calpains (Calpn) by inhibition. A rise in intracellular myocardial Ca(2+) during cardiac ischemia activates Calpn thereby causing damage to myocardial proteins, which leads to myoc...

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Detalles Bibliográficos
Autores principales:	Parameswaran, Sreejit, Sharma, Rajendra K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259361/ https://www.ncbi.nlm.nih.gov/pubmed/25486053 http://dx.doi.org/10.1371/journal.pone.0114653

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