RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)

Many biological processes are RNA-mediated, but higher-order structures for most RNAs are unknown, making it difficult to understand how RNA structure governs function. Here we describe SHAPE mutational profiling (SHAPE-MaP) that makes possible de novo and large-scale identification of RNA functiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Siegfried, Nathan A., Busan, Steven, Rice, Greggory M., Nelson, Julie A.E., Weeks, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259394/
https://www.ncbi.nlm.nih.gov/pubmed/25028896
http://dx.doi.org/10.1038/nmeth.3029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259394/
https://www.ncbi.nlm.nih.gov/pubmed/25028896
http://dx.doi.org/10.1038/nmeth.3029

Ejemplares similares