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RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)
Many biological processes are RNA-mediated, but higher-order structures for most RNAs are unknown, making it difficult to understand how RNA structure governs function. Here we describe SHAPE mutational profiling (SHAPE-MaP) that makes possible de novo and large-scale identification of RNA functiona...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259394/ https://www.ncbi.nlm.nih.gov/pubmed/25028896 http://dx.doi.org/10.1038/nmeth.3029 |