Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway

Ciclopirox olamine (CPX), a fungicide, has been demonstrated as a potential anticancer agent. However, the underlying anticancer mechanism is not well understood. Here, we found that CPX induced autophagy in human rhabdomyosarcoma (Rh30 and RD) cells. It appeared that CPX-induced autophagy was attri...

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Detalles Bibliográficos
Autores principales: Zhou, Hongyu, Shen, Tao, Shang, Chaowei, Luo, Yan, Liu, Lei, Yan, Juming, Li, Yan, Huang, Shile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259411/
https://www.ncbi.nlm.nih.gov/pubmed/25294812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259411/
https://www.ncbi.nlm.nih.gov/pubmed/25294812

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