Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia

The two transcription factors STAT5A and STAT5B are central signaling molecules in leukemias driven by Abelson fusion tyrosine kinases and they fulfill all criteria of drug targets. STAT5A and STAT5B display unique nuclear shuttling mechanisms and they have a key role in resistance of leukemic cells...

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Detalles Bibliográficos
Autores principales: Berger, Angelika, Sexl, Veronika, Valent, Peter, Moriggl, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259420/
https://www.ncbi.nlm.nih.gov/pubmed/25333255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259420/
https://www.ncbi.nlm.nih.gov/pubmed/25333255

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