Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression

The retinoblastoma (Rb) family of proteins are key regulators of cell cycle exit during development and their deregulation is associated with cancer. Rb is critical for normal retinal development and germline mutations lead to retinoblastoma making retinae an attractive system to study Rb family sig...

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Detalles Bibliográficos
Autores principales: Benavente, Claudia A., Finkelstein, David, Johnson, Dianna A., Marine, Jean-Christophe, Ashery-Padan, Ruth, Dyer, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259422/
https://www.ncbi.nlm.nih.gov/pubmed/25338120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259422/
https://www.ncbi.nlm.nih.gov/pubmed/25338120

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