Amifostine alleviates radiation-induced lethal small bowel damage via promotion of 14-3-3σ-mediated nuclear p53 accumulation

Amifostine (AM) is a radioprotector that scavenges free radicals and is used in patients undergoing radiotherapy. p53 has long been implicated in cell cycle arrest for cellular repair after radiation exposure. We therefore investigated the protective p53-dependent mechanism of AM on small bowel dama...

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Detalles Bibliográficos
Autores principales: Huang, Eng-Yen, Wang, Feng-Sheng, Chen, Yu-Min, Chen, Yi-Fan, Wang, Chung-Chi, Lin, I-Hui, Huang, Yu-Jie, Yang, Kuender D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259435/
https://www.ncbi.nlm.nih.gov/pubmed/25230151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259435/
https://www.ncbi.nlm.nih.gov/pubmed/25230151

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