Systematic dissection of the mechanisms underlying progesterone receptor downregulation in endometrial cancer

Progesterone, acting through its receptor, PR (progesterone receptor), is the natural inhibitor of uterine endometrial carcinogenesis by inducing differentiation. PR is downregulated in more advanced cases of endometrial cancer, thereby limiting the effectiveness of hormonal therapy. Our objective w...

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Detalles Bibliográficos
Autores principales: Yang, Shujie, Jia, Yichen, Liu, Xiaoyue, Winters, Christopher, Wang, Xinjun, Zhang, Yuping, Devor, Eric J., Hovey, Adriann M., Reyes, Henry D., Xiao, Xue, Xu, Yang, Dai, Donghai, Meng, Xiangbing, Thiel, Kristina W., Domann, Frederick E., Leslie, Kimberly K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259437/
https://www.ncbi.nlm.nih.gov/pubmed/25229191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259437/
https://www.ncbi.nlm.nih.gov/pubmed/25229191

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