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TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1

Transmembrane 4 L six family member 4 (TM4SF4) is a member of the tetraspanin L6 domain family. Other members of this family, TM4SF1 (also known as L6-Ag) and TM4SF5, have been shown to be upregulated in multiple tumors and involved in epithelial-to-mesenchymal transition and cell migration. However...

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Detalles Bibliográficos
Autores principales: Choi, Soo-Im, Kim, Seo-Yeon, Lee, Jaeha, Cho, Eun-Wie, Kim, In-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259440/
https://www.ncbi.nlm.nih.gov/pubmed/25344917