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Lipid binding promotes oligomerization and focal adhesion activity of vinculin

Adherens junctions (AJs) and focal adhesion (FA) complexes are necessary for cell migration and morphogenesis, and for the development, growth, and survival of all metazoans. Vinculin is an essential regulator of both AJs and FAs, where it provides links to the actin cytoskeleton. Phosphatidylinosit...

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Detalles Bibliográficos
Autores principales: Chinthalapudi, Krishna, Rangarajan, Erumbi S., Patil, Dipak N., George, Eric M., Brown, David T., Izard, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259812/
https://www.ncbi.nlm.nih.gov/pubmed/25488920
http://dx.doi.org/10.1083/jcb.201404128