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Coronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclin1 to negatively regulate antiviral innate immunity

Autophagy plays important roles in modulating viral replication and antiviral immune response. Coronavirus infection is associated with the autophagic process, however, little is known about the mechanisms of autophagy induction and its contribution to coronavirus regulation of host innate responses...

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Detalles Bibliográficos
Autores principales: Chen, Xiaojuan, Wang, Kai, Xing, Yaling, Tu, Jian, Yang, Xingxing, Zhao, Qian, Li, Kui, Chen, Zhongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259884/
https://www.ncbi.nlm.nih.gov/pubmed/25311841
http://dx.doi.org/10.1007/s13238-014-0104-6