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Radioiodination of 2,3-dimethyl-4H-furo[3,2-c]coumarin and biological evaluation in solid tumor bearing mice

Compound 2,3-dimethyl-4H-furo[3,2-c]coumarin is a coumarin derivative that could be labeled with (125)I. The process of labeling was started using 1 mg of the compound, 50 µg CAT oxidizing agent, 30 min as reaction time at pH with a yield about 95%. The (125)I-coumarin derivative was stable for abou...

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Detalles Bibliográficos
Autores principales: Abd Elhalim, S.M., Ibrahim, I.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259903/
https://www.ncbi.nlm.nih.gov/pubmed/25464192
http://dx.doi.org/10.1016/j.apradiso.2014.09.011