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Lycopene supplementation reduces TNF-α via RAGE in the kidney of obese rats

BACKGROUND: The kidney is a target organ for injuries caused by advanced glycation end products (AGEs) in obesity. The receptor of AGEs (RAGE) is proinflammatory and appears to have a role in the pathogenesis of renal disease due to obesity. OBJECTIVE: The aim was to verify the effect of obesity on...

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Detalles Bibliográficos
Autores principales: Pierine, D T, Navarro, M E L, Minatel, I O, Luvizotto, R A M, Nascimento, A F, Ferreira, A L A, Yeum, K-J, Corrêa, C R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259904/
https://www.ncbi.nlm.nih.gov/pubmed/25383746
http://dx.doi.org/10.1038/nutd.2014.39