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Time-dependent metabolomic profiling of Ketamine drug action reveals hippocampal pathway alterations and biomarker candidates

Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, has fast-acting antidepressant activities and is used for major depressive disorder (MDD) patients who show treatment resistance towards drugs of the selective serotonin reuptake inhibitor (SSRI) type. In order to better understand Ketam...

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Detalles Bibliográficos
Autores principales: Weckmann, K, Labermaier, C, Asara, J M, Müller, M B, Turck, C W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259990/
https://www.ncbi.nlm.nih.gov/pubmed/25386958
http://dx.doi.org/10.1038/tp.2014.119