Systematic Analysis of New Drug Indications by Drug-Gene-Disease Coherent Subnetworks

Drug targets and disease genes may work as driver factors at the transcriptional level, which propagate signals through gene regulatory network and cause the downstream genes' differential expression. How to analyze transcriptional response data to identify meaningful gene modules shared by bot...

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Detalles Bibliográficos
Autores principales: Wang, L, Wang, Y, Hu, Q, Li, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259999/
https://www.ncbi.nlm.nih.gov/pubmed/25390685
http://dx.doi.org/10.1038/psp.2014.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259999/
https://www.ncbi.nlm.nih.gov/pubmed/25390685
http://dx.doi.org/10.1038/psp.2014.44

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