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Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

Increased regulatory demands for pediatric drug development research have fostered interest in the use of modeling and simulation among industry and academia. Physiologically based pharmacokinetic (PBPK) modeling offers a unique modality to incorporate multiple levels of information to estimate age-...

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Detalles Bibliográficos
Autores principales: Maharaj, A R, Edginton, A N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260000/
https://www.ncbi.nlm.nih.gov/pubmed/25353188
http://dx.doi.org/10.1038/psp.2014.45