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Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development
Increased regulatory demands for pediatric drug development research have fostered interest in the use of modeling and simulation among industry and academia. Physiologically based pharmacokinetic (PBPK) modeling offers a unique modality to incorporate multiple levels of information to estimate age-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260000/ https://www.ncbi.nlm.nih.gov/pubmed/25353188 http://dx.doi.org/10.1038/psp.2014.45 |