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A New Method to Investigate How Mechanical Loading of Osteocytes Controls Osteoblasts

Mechanical loading, a potent stimulator of bone formation, is governed by osteocyte regulation of osteoblasts. We developed a three-dimensional (3D) in vitro co-culture system to investigate the effect of loading on osteocyte–osteoblast interactions. MLO-Y4 cells were embedded in type I collagen gel...

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Detalles Bibliográficos
Autores principales: Vazquez, Marisol, Evans, Bronwen A. J., Riccardi, Daniela, Evans, Sam L., Ralphs, Jim R., Dillingham, Christopher Mark, Mason, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260042/
https://www.ncbi.nlm.nih.gov/pubmed/25538684
http://dx.doi.org/10.3389/fendo.2014.00208