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Canonical structures of short CDR-L3 in antibodies

Despite sequence diversity, five out of six hypervariable loops in antibodies assume a limited number of conformations called canonical structures. Their correct identification is essential for successful prediction of antibody structure. This in turn requires regular updates of the classification o...

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Detalles Bibliográficos
Autores principales: Teplyakov, Alexey, Gilliland, Gary L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260120/
https://www.ncbi.nlm.nih.gov/pubmed/24623659
http://dx.doi.org/10.1002/prot.24559