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Tirasemtiv amplifies skeletal muscle response to nerve activation in humans

Introduction: In this study we tested the hypothesis that tirasemtiv, a selective fast skeletal muscle troponin activator that sensitizes the sarcomere to calcium, could amplify the response of muscle to neuromuscular input in humans. Methods: Healthy men received tirasemtiv and placebo in a randomi...

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Detalles Bibliográficos
Autores principales: Hansen, Richard, Saikali, Khalil G, Chou, Willis, Russell, Alan J, Chen, Michael M, Vijayakumar, Vipin, Stoltz, Randall R, Baudry, Stephane, Enoka, Roger M, Morgans, David J, Wolff, Andrew A, Malik, Fady I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260123/
https://www.ncbi.nlm.nih.gov/pubmed/24634285
http://dx.doi.org/10.1002/mus.24239