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Chemotherapy induced microsatellite instability and loss of heterozygosity in chromosomes 2, 5, 10, and 17 in solid tumor patients

BACKGROUND: The inevitable side effects of the currently used chemotherapy are associated with serious syndromes. Genotoxic effects and consequent genetic instability may play an important role in these syndromes. The aim of the study was to evaluate chemotherapy-related microsatellite instability (...

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Detalles Bibliográficos
Autores principales: Kamat, Nasir, Khidhir, Mohammed A, Hussain, Sabir, Alashari, Mouied M, Rannug, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260186/
https://www.ncbi.nlm.nih.gov/pubmed/25493073
http://dx.doi.org/10.1186/s12935-014-0118-4