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Coapplication of Lidocaine and Membrane-Impermeable Lidocaine Derivative QX-222 Produces Divergent Effects on Evoked and Spontaneous Nociceptive Behaviors in Mice

The present study was aimed at investigating the analgesic properties of a combination of lidocaine and QX-222 and its effects on evoked pain behavior (complete Freund's adjuvant-induced allodynia and hyperalgesia in inflammatory condition) and spontaneous pain behavior (formalin-induced acute...

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Detalles Bibliográficos
Autores principales: Hu, Si-Ping, Zhao, Jing-Jing, Wang, Wei-Xing, Liu, Yang, Wu, He-Fen, Chen, Chao, Yu, Liang, Gui, Jing-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260428/
https://www.ncbi.nlm.nih.gov/pubmed/25506595
http://dx.doi.org/10.1155/2014/628729