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Locus heterogeneity disease genes encode proteins with high interconnectivity in the human protein interaction network

Mutations in genes potentially lead to a number of genetic diseases with differing severity. These disease genes have been the focus of research in recent years showing that the disease gene population as a whole is not homogeneous, and can be categorized according to their interactions. Locus heter...

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Detalles Bibliográficos
Autores principales: Keith, Benjamin P., Robertson, David L., Hentges, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260505/
https://www.ncbi.nlm.nih.gov/pubmed/25538735
http://dx.doi.org/10.3389/fgene.2014.00434