Synthesis of Bicyclic Guanidines via Cascade Hydroamination/Michael Additions of Mono-N-acryloylpropargylguanidines

[Image: see text] A cascade silver(I)-catalyzed hydroamination/Michael addition sequence has been developed to deliver highly substituted bicyclic guanidines. This transformation gives rise to geometrically and constitutionally stable ene–guanidines and generates a remote stereocenter with moderate...

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Detalles Bibliográficos
Autores principales: Kwon, Ki-Hyeok, Serrano, Catherine M., Koch, Michael, Barrows, Louis R., Looper, Ryan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260634/
https://www.ncbi.nlm.nih.gov/pubmed/25393831
http://dx.doi.org/10.1021/ol502691w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260634/
https://www.ncbi.nlm.nih.gov/pubmed/25393831
http://dx.doi.org/10.1021/ol502691w

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