Photoredox Catalysis in a Complex Pharmaceutical Setting: Toward the Preparation of JAK2 Inhibitor LY2784544

[Image: see text] We report a detailed investigation into the application of visible light-mediated photocatalysis to a challenging bond construction in a complex pharmaceutical target. The optimized reaction allowed the direct coupling of N-methylmorpholine with an unfunctionalized pyridazine in go...

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Detalles Bibliográficos
Autores principales: Douglas, James J., Cole, Kevin P., Stephenson, Corey R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260666/
https://www.ncbi.nlm.nih.gov/pubmed/25356724
http://dx.doi.org/10.1021/jo502288q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260666/
https://www.ncbi.nlm.nih.gov/pubmed/25356724
http://dx.doi.org/10.1021/jo502288q

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