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CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells

Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are characterised by an unusual and tightly regulated cell cycle that has been shown to be important for the maintenance of a pluripotent phenotype. Cyclin-dependant kinase 1 (CDK1) is a key player in cell cycle regulation...

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Detalles Bibliográficos
Autores principales: Neganova, I, Tilgner, K, Buskin, A, Paraskevopoulou, I, Atkinson, S P, Peberdy, D, Passos, J F, Lako, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260724/
https://www.ncbi.nlm.nih.gov/pubmed/25375373
http://dx.doi.org/10.1038/cddis.2014.464