Cargando…
CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells
Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are characterised by an unusual and tightly regulated cell cycle that has been shown to be important for the maintenance of a pluripotent phenotype. Cyclin-dependant kinase 1 (CDK1) is a key player in cell cycle regulation...
Autores principales: | Neganova, I, Tilgner, K, Buskin, A, Paraskevopoulou, I, Atkinson, S P, Peberdy, D, Passos, J F, Lako, M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260724/ https://www.ncbi.nlm.nih.gov/pubmed/25375373 http://dx.doi.org/10.1038/cddis.2014.464 |
Ejemplares similares
-
Endothelial Differentiation G Protein‐Coupled Receptor 5 Plays an Important Role in Induction and Maintenance of Pluripotency
por: Neganova, Irina, et al.
Publicado: (2019) -
The recent advances in the mathematical modelling of human pluripotent stem cells
por: Wadkin, L. E., et al.
Publicado: (2020) -
Current understanding of genomic stability maintenancein pluripotent stem cells: Genomic stability maintenance in pluripotent stem cells
por: Zheng, Ping
Publicado: (2022) -
A Novel Role for miR‐1305 in Regulation of Pluripotency‐Differentiation Balance, Cell Cycle, and Apoptosis in Human Pluripotent Stem Cells
por: Jin, Shibo, et al.
Publicado: (2016) -
A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells
por: Wadkin, L. E., et al.
Publicado: (2021)