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CBAP promotes thymocyte negative selection by facilitating T-cell receptor proximal signaling

T-cell receptor (TCR)-transduced signaling is critical to thymocyte development at the CD4/CD8 double-positive stage, but the molecules involved in this process are not yet fully characterized. We previously demonstrated that GM-CSF/IL-3/IL-5 receptor common β-chain-associated protein (CBAP) modulat...

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Detalles Bibliográficos
Autores principales: Ho, K-C, Chiang, Y-J, Lai, A C-Y, Liao, N-S, Chang, Y-J, Yang-Yen, H-F, Yen, J J-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260732/
https://www.ncbi.nlm.nih.gov/pubmed/25393474
http://dx.doi.org/10.1038/cddis.2014.474