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The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes

The Hippo pathway fulfills a crucial function in controlling the balance between proliferation, differentiation and apoptosis in cells. Recent studies showed that G protein-coupled receptors (GPCRs) serve as upstream regulators of Hippo signaling, that either activate or inactivate the Hippo pathway...

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Detalles Bibliográficos
Autores principales: Wennmann, D O, Vollenbröker, B, Eckart, A K, Bonse, J, Erdmann, F, Wolters, D A, Schenk, L K, Schulze, U, Kremerskothen, J, Weide, T, Pavenstädt, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260734/
https://www.ncbi.nlm.nih.gov/pubmed/25393475
http://dx.doi.org/10.1038/cddis.2014.476