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Activation of volume-sensitive outwardly rectifying chloride channel by ROS contributes to ER stress and cardiac contractile dysfunction: involvement of CHOP through Wnt

Endoplasmic reticulum (ER) stress occurring in stringent conditions is critically involved in cardiomyocytes apoptosis and cardiac contractile dysfunction (CCD). However, the molecular machinery that mediates cardiac ER stress and subsequent cell death remains to be fully deciphered, which will hope...

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Detalles Bibliográficos
Autores principales: Shen, M, Wang, L, Wang, B, Wang, T, Yang, G, Shen, L, Guo, X, Liu, Y, Xia, Y, Jia, L, Wang, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260737/
https://www.ncbi.nlm.nih.gov/pubmed/25412307
http://dx.doi.org/10.1038/cddis.2014.479