Inhibition of apoptosis signal-regulating kinase 1 enhances endochondral bone formation by increasing chondrocyte survival

Endochondral ossification is the result of chondrocyte differentiation, hypertrophy, death and replacement by bone. The careful timing and progression of this process is important for normal skeletal bone growth and development, as well as fracture repair. Apoptosis Signal-Regulating Kinase 1 (ASK1)...

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Detalles Bibliográficos
Autores principales: Eaton, G J, Zhang, Q-S, Diallo, C, Matsuzawa, A, Ichijo, H, Steinbeck, M J, Freeman, T A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260738/
https://www.ncbi.nlm.nih.gov/pubmed/25393478
http://dx.doi.org/10.1038/cddis.2014.480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260738/
https://www.ncbi.nlm.nih.gov/pubmed/25393478
http://dx.doi.org/10.1038/cddis.2014.480

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