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PKCη promotes senescence induced by oxidative stress and chemotherapy

Senescence is characterized by permanent cell-cycle arrest despite continued viability and metabolic activity, in conjunction with the secretion of a complex mixture of extracellular proteins and soluble factors known as the senescence-associated secretory phenotype (SASP). Cellular senescence has b...

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Detalles Bibliográficos
Autores principales: Zurgil, U, Ben-Ari, A, Atias, K, Isakov, N, Apte, R, Livneh, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260739/
https://www.ncbi.nlm.nih.gov/pubmed/25412309
http://dx.doi.org/10.1038/cddis.2014.481