Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells

Benzyl isothiocyanate (BITC), a dietary isothiocyanate derived from cruciferous vegetables, inhibits the proliferation of colorectal cancer cells, most of which overexpress β-catenin as a result of mutations in the genes for adenomatous polyposis coli or mutations in β-catenin itself. Because nuclea...

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Detalles Bibliográficos
Autores principales: Abe, N, Hou, D-X, Munemasa, S, Murata, Y, Nakamura, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260753/
https://www.ncbi.nlm.nih.gov/pubmed/25412312
http://dx.doi.org/10.1038/cddis.2014.495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260753/
https://www.ncbi.nlm.nih.gov/pubmed/25412312
http://dx.doi.org/10.1038/cddis.2014.495

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