The NF2 Tumor Suppressor Regulates Microtubule-Based Vesicle Trafficking via a Novel Rac, MLK and p38(SAPK) Pathway

Neurofibromatosis Type 2 patients develop schwannomas, meningiomas and ependymomas resulting from mutations in the tumor suppressor gene, NF2, encoding a membrane-cytoskeleton adaptor protein called merlin. Merlin regulates contact inhibition of growth and controls the availability of growth factor...

Descripción completa

Detalles Bibliográficos
Autores principales: Hennigan, Robert F., Moon, Chandra A., Parysek, Linda M., Monk, Kelly R., Morfini, Gerardo, Berth, Sarah, Brady, Scott, Ratner, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260777/
https://www.ncbi.nlm.nih.gov/pubmed/22525268
http://dx.doi.org/10.1038/onc.2012.135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260777/
https://www.ncbi.nlm.nih.gov/pubmed/22525268
http://dx.doi.org/10.1038/onc.2012.135

Ejemplares similares