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The NF2 Tumor Suppressor Regulates Microtubule-Based Vesicle Trafficking via a Novel Rac, MLK and p38(SAPK) Pathway
Neurofibromatosis Type 2 patients develop schwannomas, meningiomas and ependymomas resulting from mutations in the tumor suppressor gene, NF2, encoding a membrane-cytoskeleton adaptor protein called merlin. Merlin regulates contact inhibition of growth and controls the availability of growth factor...
Autores principales: | Hennigan, Robert F., Moon, Chandra A., Parysek, Linda M., Monk, Kelly R., Morfini, Gerardo, Berth, Sarah, Brady, Scott, Ratner, Nancy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260777/ https://www.ncbi.nlm.nih.gov/pubmed/22525268 http://dx.doi.org/10.1038/onc.2012.135 |
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