Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression

BACKGROUND: DNA methylation is thought to play an important role in the regulation of mammalian gene expression, partly based on the observation that a lack of CpG island methylation in gene promoters is associated with high transcriptional activity. However, the CpG island methylation level only ac...

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Detalles Bibliográficos
Autores principales: Edgar, Rachel, Tan, Powell Patrick Cheng, Portales-Casamar, Elodie, Pavlidis, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260796/
https://www.ncbi.nlm.nih.gov/pubmed/25493099
http://dx.doi.org/10.1186/1756-8935-7-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260796/
https://www.ncbi.nlm.nih.gov/pubmed/25493099
http://dx.doi.org/10.1186/1756-8935-7-28

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