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Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression
BACKGROUND: DNA methylation is thought to play an important role in the regulation of mammalian gene expression, partly based on the observation that a lack of CpG island methylation in gene promoters is associated with high transcriptional activity. However, the CpG island methylation level only ac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260796/ https://www.ncbi.nlm.nih.gov/pubmed/25493099 http://dx.doi.org/10.1186/1756-8935-7-28 |