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A Nutrient-Driven tRNA Modification Alters Translational Fidelity and Genome-wide Protein Coding across an Animal Genus

Natural selection favors efficient expression of encoded proteins, but the causes, mechanisms, and fitness consequences of evolved coding changes remain an area of aggressive inquiry. We report a large-scale reversal in the relative translational accuracy of codons across 12 fly species in the Droso...

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Detalles Bibliográficos
Autores principales: Zaborske, John M., Bauer DuMont, Vanessa L., Wallace, Edward W. J., Pan, Tao, Aquadro, Charles F., Drummond, D. Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260829/
https://www.ncbi.nlm.nih.gov/pubmed/25489848
http://dx.doi.org/10.1371/journal.pbio.1002015