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CD73 Is Dispensable for the Regulation of Inflationary CD8(+) T-Cells after Murine Cytomegalovirus Infection and Adenovirus Immunisation

The ecto-5'-nucleotidase (CD73) is expressed by T-cell subsets, myeloid derived suppressive cells and endothelial cells. It works in conjunction with CD39 to regulate the formation and degradation of adenosine in vivo. Adenosine has previously been shown to suppress the proliferation and cytoki...

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Detalles Bibliográficos
Autores principales: Sims, Stuart, Colston, Julia, Emery, Vince, Klenerman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260835/
https://www.ncbi.nlm.nih.gov/pubmed/25490556
http://dx.doi.org/10.1371/journal.pone.0114323