Computational Construction of Antibody–Drug Conjugates Using Surface Lysines as the Antibody Conjugation Site and a Non-cleavable Linker

Antibody–drug conjugates (ADCs) constitute a category of anticancer targeted therapy that has gathered great interest during the last few years because of their potential to kill cancer cells while causing significantly fewer side effects than traditional chemotherapy. In this paper, a process of co...

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Detalles Bibliográficos
Autores principales: Filntisi, Arianna, Vlachakis, Dimitrios, Matsopoulos, George K, Kossida, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260860/
https://www.ncbi.nlm.nih.gov/pubmed/25506200
http://dx.doi.org/10.4137/CIN.S19222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260860/
https://www.ncbi.nlm.nih.gov/pubmed/25506200
http://dx.doi.org/10.4137/CIN.S19222

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