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Computational Construction of Antibody–Drug Conjugates Using Surface Lysines as the Antibody Conjugation Site and a Non-cleavable Linker
Antibody–drug conjugates (ADCs) constitute a category of anticancer targeted therapy that has gathered great interest during the last few years because of their potential to kill cancer cells while causing significantly fewer side effects than traditional chemotherapy. In this paper, a process of co...
Autores principales: | Filntisi, Arianna, Vlachakis, Dimitrios, Matsopoulos, George K, Kossida, Sophia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260860/ https://www.ncbi.nlm.nih.gov/pubmed/25506200 http://dx.doi.org/10.4137/CIN.S19222 |
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