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Pharmacodynamic and Therapeutic Investigation of Focused Ultrasound-Induced Blood-Brain Barrier Opening for Enhanced Temozolomide Delivery in Glioma Treatment

Focused ultrasound (FUS) exposure with the presence of microbubbles has been shown to transiently open the blood-brain barrier (BBB), and thus has potential to enhance the delivery of various kinds of therapeutic agents into brain tumors. The purpose of this study was to assess the preclinical thera...

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Detalles Bibliográficos
Autores principales: Liu, Hao-Li, Huang, Chiung-Yin, Chen, Ju-Yu, Wang, Hay-Yan Jack, Chen, Pin-Yuan, Wei, Kuo-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260869/
https://www.ncbi.nlm.nih.gov/pubmed/25490097
http://dx.doi.org/10.1371/journal.pone.0114311