Comparison of Neutralizing Antibody Responses Elicited from Highly Diverse Polyvalent Heterotrimeric HIV-1 gp140 Cocktail Immunogens versus a Monovalent Counterpart in Rhesus Macaques

Eliciting neutralizing antibodies capable of inactivating a broad spectrum of HIV-1 strains is a major goal of HIV-1 vaccine design. The challenge is that envelopes (Envs) of circulating viruses are almost certainly different from any Env used in a vaccine. A novel immunogen composed of a highly div...

Descripción completa

Detalles Bibliográficos
Autores principales: Bowles, Emma J., Schiffner, Torben, Rosario, Maximillian, Needham, Gemma A., Ramaswamy, Meghna, McGouran, Joanna, Kessler, Benedikt, LaBranche, Celia, McMichael, Andrew J., Montefiori, David, Sattentau, Quentin J., Hanke, Tomáš, Stewart-Jones, Guillaume B. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260879/
https://www.ncbi.nlm.nih.gov/pubmed/25490553
http://dx.doi.org/10.1371/journal.pone.0114709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260879/
https://www.ncbi.nlm.nih.gov/pubmed/25490553
http://dx.doi.org/10.1371/journal.pone.0114709

Ejemplares similares