By-Product Formation in Repetitive PCR Amplification of DNA Libraries during SELEX

The selection of nucleic acid aptamers is an increasingly important approach to generate specific ligands binding to virtually any molecule of choice. However, selection-inherent amplification procedures are prone to artificial by-product formation that prohibits the enrichment of target-recognizing...

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Detalles Bibliográficos
Autores principales: Tolle, Fabian, Wilke, Julian, Wengel, Jesper, Mayer, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260880/
https://www.ncbi.nlm.nih.gov/pubmed/25490402
http://dx.doi.org/10.1371/journal.pone.0114693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260880/
https://www.ncbi.nlm.nih.gov/pubmed/25490402
http://dx.doi.org/10.1371/journal.pone.0114693

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