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By-Product Formation in Repetitive PCR Amplification of DNA Libraries during SELEX
The selection of nucleic acid aptamers is an increasingly important approach to generate specific ligands binding to virtually any molecule of choice. However, selection-inherent amplification procedures are prone to artificial by-product formation that prohibits the enrichment of target-recognizing...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260880/ https://www.ncbi.nlm.nih.gov/pubmed/25490402 http://dx.doi.org/10.1371/journal.pone.0114693 |