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An Acyl-CoA Synthetase in Mycobacterium tuberculosis Involved in Triacylglycerol Accumulation during Dormancy

Latent infection with dormant Mycobacterium tuberculosis is one of the major reasons behind the emergence of drug-resistant strains of the pathogen worldwide. In its dormant state, the pathogen accumulates lipid droplets containing triacylglycerol synthesized from fatty acids derived from host lipid...

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Detalles Bibliográficos
Autores principales: Daniel, Jaiyanth, Sirakova, Tatiana, Kolattukudy, Pappachan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260918/
https://www.ncbi.nlm.nih.gov/pubmed/25490545
http://dx.doi.org/10.1371/journal.pone.0114877