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PED/PEA-15 Inhibits Hydrogen Peroxide-Induced Apoptosis in Ins-1E Pancreatic Beta-Cells via PLD-1

The small scaffold protein PED/PEA-15 is involved in several different physiologic and pathologic processes, such as cell proliferation and survival, diabetes and cancer. PED/PEA-15 exerts an anti-apoptotic function due to its ability to interfere with both extrinsic and intrinsic apoptotic pathways...

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Detalles Bibliográficos
Autores principales: Fiory, Francesca, Parrillo, Luca, Raciti, Gregory Alexander, Zatterale, Federica, Nigro, Cecilia, Mirra, Paola, Falco, Roberta, Ulianich, Luca, Di Jeso, Bruno, Formisano, Pietro, Miele, Claudia, Beguinot, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260953/
https://www.ncbi.nlm.nih.gov/pubmed/25489735
http://dx.doi.org/10.1371/journal.pone.0113655