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Linear Free Energy Relationships Reveal Structural Changes in Hydrogen-Bonded Host–Guest Interactions
[Image: see text] Hydrogen bond strength in host–guest systems is modulated by many factors including preorganization, steric effects, and electronic effects. To investigate how electronic effects impact barbiturate binding in bifurcated Hamilton receptors, a library of receptors with differing elec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260963/ https://www.ncbi.nlm.nih.gov/pubmed/25412431 http://dx.doi.org/10.1021/jo502325w |