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CXCL12-γ in Primary Tumors Drives Breast Cancer Metastasis

Compelling evidence shows that chemokine CXCL12 drives metastasis in multiple malignancies. Similar to other key cytokines in cancer, CXCL12 exists as several isoforms with distinct biophysical properties that may alter signaling and functional outputs. However, effects of CXCL12 isoforms in cancer...

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Detalles Bibliográficos
Autores principales: Ray, Paramita, Stacer, Amanda C., Fenner, Joseph, Cavnar, Stephen P., Meguiar, Kaille, Brown, Martha, Luker, Kathryn E., Luker, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261050/
https://www.ncbi.nlm.nih.gov/pubmed/24909174
http://dx.doi.org/10.1038/onc.2014.157